Buster Moon is sure that the cast at the New Moon Theater is ready to perform for a bigger audience, but when a talent scout is not impressed by the show, he decides to take everyone to the big city to audition for her boss.
In Charleston, South Carolina, a young business entrepreneur, newly out as gay, starts his own junior talent agency and signs a thirteen-year-old aspiring drag queen as his first client.
As eighth-graders Mackenzie Little-Armstrong and her nemesis Ruby vie to be Social Chair of Bel-Air Middle School, Ruby employs a secret weapon, but Mac is determined to gain fame by being as good a talent agent as her mother.
The friendship between Mackenzie Little-Armstrong, Evangelina Becks, Coco Kingsley, and Emily Skyler becomes strained when Mac's efforts to help her friends achieve stardom do not go exactly as planned.
Eighth-grader Kristy Armstrong decides to make her mark at clique-ruled Bel Air Middle School by following in her top talent agent-mother's footsteps and catapulting a new student into stardom, which jeopardizes her relationships with best friends Marisol and Dee.