Winry, Ed, and Alphonse go south in Search of Izumi Curtis, the master alchemist; however, an encounter with a pickpocket in the town of Rush Valley heads them down a different path.
Hohenhein has the opportunity to stop the "father" who rules over Central City, but surprise may not be enough to help him defeat the powerful homunculus.
Ed struggles to overcome his mistrust of his estranged father in order to receive help in fighting Pride, while Mustang leads an attack in Central City.
Old friends and enemies reappear, and Edward Elric does all he can to ensure the safety of Automail engineer Wiry, who is being held hostage; and Hawkeye learns a startling truth about President Bradley's son.
Edward Elric and his brother Alphonse try to discover why they no longer possess alchemical powers, traveling to fort Briggs in the frozen north, and Scar and Kimblee face each other on a moving train.
State alchemist Edward Elric seeks the legendary Philosopher's Stone to heal himself and his brother Alphonse, who were injured in a ritual. During his quest, Ed returns to Resembool and sees his father for the first time in many years. He learns a vital fact about the ritual he and Alphonse tried that led to their injuries.
