Twelve-year-old David has conflicting feelings when his father, who taught him to ride the horses he loves so much, returns to spend Thanksgiving Day with the family after being gone for a year.
With the help of her veterinarian grandmother and the other volunteers at the Wild at Heart Animal Clinic, eleven-year-old Maggie rescues sick puppies from an illegal puppy mill.
Adjusting to middle school becomes easier for twelve-year-old Maggie when she finds that her biology teacher, who is blind, can learn a few things from her about working with his guide dog.
Seeing Jane's dog, Yum-Yum, help cheer up children in a cancer ward makes Zoe think about having her puppy, Sneakers, trained to do therapy, too, especially when Yum-Yum becomes very ill.
Brenna, one of the volunteers at the Wild at Heart animal clinic, is horrified to find a dog caught in a trap in the local nature preserve, but subsequent events prove that every story has two sides.
After assisting with her own cat's emergency surgery, Sunita decides she can no longer work with animals and accepts an internship at a lab, unaware that the research conducted there includes animal testing.
When he and the other volunteers at Dr. Mac's veterinary clinic go to help out at Quinn's Stables, David makes several serious mistakes and must prove he can be trusted before Mr. Quinn will let him even be around the spirited horse that David wants to ride.
Adjusting to middle school becomes easier for twelve-year-old Maggie when she finds that her biology teacher, who is blind, can learn a few things from her about working with his guide dog.