Vanessa's sister Virginia is in a "wolfish" mood--growling, howling and acting very strange. Vanessa tries everything she can think of to cheer her up, but nothing seems to work. Loosely based on the relationship between author Virginia Woolf and her sister, painter Vanessa Bell.
Illustrations and simple text describe different reasons for being grumpy, such as eating "grown-up" cereal, getting a boring birthday present, doing chores, and being touched by your brother or sister.