The heroes of the Ultimates and S.H.I.E.L.D. face Reed Richards' Children of Tomorrow who have destroyed Europe and Washington, D.C., and are on their way to taking over the whole Earth.
In the Southeast Asian Republic, a new mutant uprising of a group of rebels known as The People threatens the stability of world powers across the globe. S.H.I.E.L.D.'s Hawkeye is sent behind enemy lines to find out what makes The People's mutant serum so effective.
