As the founders of the Chicagoland Detective Agency, a haiku-writing girl and a boy with a talking dog have more than enough cases on their hands (and paws) when a friend vanishes, a mummy's amulet disappears, and an evil scientist stalks human brains and hearts.
Megan Yamamura, who has a knack for investigation, tries to stop the students at a summer preparatory school from being turned into mindless automatons by the principal, the cafeteria lady, and the school psychiatrist.