Cannon fire! That's what Jack and Annie hear when the magic tree house whisks them back to the time of the American Civil War. There they meet a famous nurse named Clara Barton and do their best to help wounded soldiers. It is the hardest journey in time yet - and one that will make the most difference to their own lives!.
Eight-year-old Jack, his seven-year-old sister, Annie, and Peanut the mouse ride in a tree house to the Amazon rain forests, where they encounter giant ants, flesh-eating piranhas, hungry crocodiles, and wild jaguars.
Jack and Annie travel 500 years back in time to Florence, Italy, and spend a day helping Leonardo da Vinci in the hope of learning another secret of happiness.