Zack feels that a supernatural force is at work in his apartment when he encounters floating television sets, pancakes that flip by themselves, and a ghost named Wanda.
Zack's science fair partner, Andrew, has always boasted and told lies, but now each time Andrew fibs his butt gets bigger, and Zack must find a way to help before their science project is destroyed.
Zack succumbs to Rhyme Disease after being bitten by a tick during a class trip to Central Park, which causes him to speak only in rhymes and to float like a helium balloon.