While sitting in detention, George and Harold accidentally create an army of evil talking toilets, and Principal Krupp's alter ego, Captain Underpants, has to save the world from it.
George and Harold's attempts to hypnotize their teacher results in the creation of the monstrous Wedgie Woman, who sets out to rule the world by getting rid of Captain Underpants.
While sitting in detention, George and Harold accidentally create an army of evil talking toilets, and Principal Krupp's alter ego, Captain Underpants, has to save the world from it.
When George and Harold hypnotize their principal into thinking that he is the superhero Captain Underpants, he leads them to the lair of the nefarious Dr. Diaper, where they must defeat his evil robot henchmen.
Crackers and Sulu, the Bionic Hamster, finds themselves in a backwards universe where George and Harold's own evil twins rule the school with the help of the wicked Captain Blunderpants.
George and Harold are not bad kids. They just like to "liven things up" for everyone. Unfortunately, their thoughtful jokes sometimes get them into a lot of trouble.
