Suzanne is delighted when her Great-Aunt Deidra leaves her Newfoundland, Beatrice, to Suzanne's mother, but Beatrice is old, slow, and has serious stomach issues which Suzanne and Anna must try to fix before Dad sends another dog away.
When Joe goes to live with his father across town and must leave behind his beloved pet rabbit, his friends Anna and Suzanne try to take care of it for him, but when the rabbit becomes ill and then Joe follows suit, the girls are certain that both will die unless they are reunited.
When their naughty cat disappears while being disciplined for bringing home the head of the vicar's most expensive koi carp, three siblings suspect a kidnapping and start an investigation.
After a long pestering campaign, nine-year-old Anna and her younger brother Tom finally get a pair of hamsters, but when the pets are found mysteriously dead, the siblings and neighbor Suzanne launch an investigation throughout their neighborhood.