Mad scientist Petty Potts asks her neighbors, twins Josh and Danny, to help with her experiments and when her SWITCH spray turns them into flies, they are able to investigate the sabotage of their mother's garden.
Discusses the history of flies, examines their family trees, anatomy, life cycles, predators, and prey, and looks at myths and facts about the insects, and how to get rid of them.
When Buzz captures a fly to enter in The Amazing Pet Show, his parents and the judges tell him that a fly cannot be a pet, but Fly Guy proves them wrong.
While riding in the car with Buzz and his father, Fly Guy gets blown out of the window and finds himself riding in a truck, then a boat, a train, an airplane, and maybe even a rocket.
