Mary Jekyll struggles to make ends meet after the death of her parents. As she dives into the secrets of her father's past, she finds herself on the search for her father's former friend, Edward Hyde. With the help of Sherlock Holmes and Dr. Watson, Mary uncovers a secret society of crazed scientists and the Frankenstein women who have been created through frightening experiments. Together, they are determined to bring an end to the society before they do anymore monstrous deeds.