In 1539, Kitty Tylney and her best friend Cat Howard--the audacious, self-proclaimed "Queen of Misrule"--both servants to the Duchess of Norfolk, move to the court of King Henry VIII. When Cat (Catharine Howard) becomes Henry's fifth wife, and Queen of England, Kitty must learn to navigate the complexities and dangers of the royal court and her best friend, now the Queen, whom she does not always recognize because her motives and personality have changed.