Before Sally's Nana can finish filling in the faces on a row of paper dolls which she has cut out, the five sisters are whisked off on a series of extraordinary adventures.
Liza hates third grade because she is separated from her best friend and she has mean Mrs. Rumford as her teacher, until she begins to make new friends.
Tired of being considered predictable, Louise decides to make some changes in her life, but she finds out that her family and friends miss the "old Louise"-- and so does she.
Best friends Mandy and Mimi have a scary time when their eagerness to see mummies leads them to sneak into the new museum exhibit a week before it opens.