Ten-year-old Polly Winkler just wants to be normal, but it looks like her goal is going to remain out of reach when her dad decides to marry Veronica Kreep, the mother of the weirdest family in town.
Polly is about to start the fifth grade when she learns that she will be in the same classroom as her mad scientist stepbrother, Damon Kreep, and Polly is afraid of how Damon's strange experiments and behavior will reflect on her.
Polly, having been befriended by the snottiest girl in school, Denise Dunleavy, worries that Denise will find out about her supernatural stepfamily and tries to find a way to cure Denise's crush on her stepbrother.
Polly Winkler, left alone with her weird new step-siblings after her dad marries their mother, Veronica Kreep, and goes off on a honeymoon, is surprised to find she has something in common with them--the conviction that the baby-sitter has to go.
Now that Polly and the Kreeps are officially family, their parents have left the kids with a nanny with a mean streak. The Kreeps may be creepy, but this nanny has got to go!.
As her father prepares to marry their new neighbor, Veronica Kreep, Polly tries to convince him that there is something sinister and strange about Veronica and her family.
Polly's mad-scientist stepbrother, Damon, spends hours in his creepy basement laboratory preparing to enter the school science fair. Polly doesn't know what is worse, that Damon is clearly up to no good with his experiment or that he might actually win first place at the fair.
Polly wants to join the soccer team to have some normal fun, away from her weird new step family. But her witchy stepmother, Veronica Kreep, is determined to be Polly's biggest fan.