After the multiverse was destroyed, the only realm left was Battleworld, run by Victor von Doom. Final exams are approaching Battleworld's Institute for Gifted Youths, but the Runaways, a group of gifted, sometimes superpowered children, do not take kindly to finding out their beloved headmaster is a supervillain. Running away, the kids end up in the Wild West domain of 1872, where they are chased by the Winter Soldier, and Molly Hayes gets a cowboy hat.