After escaping the ruthless desperados, master-of-disguise P.K. Pinkerton has now set up a Private Eye business in Virginia City and is ready when a young maid named Martha approaches him for help in escaping a killer.
A cloud of nanoparticles programmed as a predator and capable of self-reproduction escapes from a Nevada laboratory and makes the human population its target.
Follows ninety-two-year-old Anna Madrigal, the legendary transgender landlady of 28 Barbary Lane, as she joins her former tenant Brian on a road trip to Nevada where she attends to unfinished business she has long avoided.
When Jack Osborne is befriended by his school's custodian and a Basque girl, he begins to adjust to his family's sudden move to Elko, Nevada, after entering the Witness Security Program, but the drug cartel against which his father will testify is determined to track them down.