Cromartie High's star contender for the All-Japan Kingpin Championship is trapped in America, forcing the team to replace him with Kamiyama, who hopes to win the title of top thug in Japan.
George and Harold's attempts to hypnotize their teacher results in the creation of the monstrous Wedgie Woman, who sets out to rule the world by getting rid of Captain Underpants.
When her substitute teacher realizes she is struggling in math, Judy is sent to a math tutor at the local college and soon is completely into the spirit of college life.
Wild things happen at the South Middle School when Milo's science project, Henrietta the chicken, becomes the hockey team's mascot and their only chance for a winning season.
Bailey Morgan's double life as ordinary high school student by day and ancient mystical being by night begins to take its toll, until she meets the rest of the Sidhe and is drawn into their otherworldly web.