Sherlock Holmes and his apprentice Mary Russell travel to Jerusalem where they attempt to find the person responsible for a recent rash of brutal murders.
When several members of a feminist Christian sect in London are murdered, Mary Russell, with the help of her friend Sherlock Holmes, begins to investigate and finds herself in danger.
Mary Russell, wife of Sherlock Holmes, investigates the murder of their archeologist friend, Dorothy Ruskin, who had given them an inlaid box with a tattered roll of papyrus inside, supposedly written by Mary Magdalene.
Mary Russell returns to Sussex with her husband, Sherlock Holmes, and is reunited with Damian Adler, who seeks Russell's help to locate his missing wife and child, which leads Russell onto the trail of a killer.
Allen Carmichael, having used the skills he learned as a soldier in Vietnam to build a career rescuing children and women from abusive men, is ready to retire from the game when he discovers evidence that leads him to believe his last case, in which he removed a twelve-year-old boy from his father, requires further attention.
In 1915, fifteen-year-old Mary Russell meets the retired Sherlock Holmes and impresses the legendary sleuth with her intellect. They work a case together to find the kidnapped daughter of an American senator, while trying to avoid an adversary determined to end their partnership.
Sherlock Holmes and his apprentice Mary Russell travel to Jerusalem where they attempt to find the person responsible for a recent rash of brutal murders.