While their family is away, Harold and Chester, a dog and a cat, are boarded at Chateau Bow-Wow where Chester becomes increasingly alarmed by the strange behavior of his fellow guests and the sudden disappearance of one of them.
When seemingly unrelated and strange events start to happen and a precious Vermeer painting disappears, eleven-year-olds Petra and Calder combine their talents to solve an international art scandal.
While visiting their friend Wallis and her adopted daughter on Mount Desert Island, Maine, Josh, Dink, and Ruth Rose investigate why three white wolf cubs were stolen, and by whom.
The traditional River Heights Thanksgiving feast festivities are being threatened when Thanksgiving food all around town begins to disappear and the Clue Crew must rush to save the holiday.