While on vacation, Mrs. LaRue receives letters from her dog Ike who has been falsely accused of harming the neighbor's cats and is trying to clear his name.
When his mother is stolen from her tomb, Ramose, a 4000-year-old mummy, tries to find her in the Egyptian desert, aboard an ocean liner, and in New York City's Metropolitan Museum.
Third-grader Gordie is not only having problems with his best friend, he also has to teach his not-so-smart dog some tricks for the upcoming school talent show.