Chester the cat is more than ever convinced that Bunnicula is a vampire when there is a harvest of white vegetables on the morning after the night that Bunnicula was probably wandering through the neighborhood.
With help from his Uncle Harold, who wrote books about Bunnicula, Howie the wire-haired dachshund writes a story in which he saves the world from a science experiment gone awry.
Rex's parents are adopting a baby, and Rex doesn't like the idea at all. Suppose his parents are so busy with the new baby they forget about her? So she comes up with a plan. If she can be the perfect big sister, her parents will have to pay attention to her. The trouble is, being the perfect big sister is a lot of work, and it doesn't leave time or much else--like her best friend, Pinky.
The pets in the Monroe household become concerned when they see a poster of the Amazing Karlovsky pulling a rabbit out of a hat that looks very much like their vampire bunny Bunnicula.
Four students who do not fit in at their small-town middle school decide to create a third party for the student council elections to represent all students who have ever been called names.