After Miss Clark brings a new class pet, Dexter the hamster, into the classroom, Dexter soon escapes from his cage and it is up to brother and sister mice, Molly and Jake, to show him how to survive when you're not someone's pet.
Molly and Jake, brother and sister mice who live inside the wall of Miss Clark's classroom, face a series of tests to their survival skills after taking escaped class pet Dexter, a gerbil, into their care.