Professor Pippy P. Poopypants comes to Jerome Horwitz Elementary School to teach science, and goes off the deep end because students make fun of his name, leaving Captain Underpants to save the school from the professor's perilous plot.
A snotty situation ensues when Melvin Sneedley, an academically-gifted student, turns into the Bionic Booger Boy and must be stopped by George, Harold, and Captain Underpants.
Tired of following the strict rules of their grumpy replacement principal, second-grader A.J. and his classmates try to find a way to bring back eccentric but lovable Principal Klutz, who was fired for bringing a wild turkey to the school's Thanksgiving Day assembly.
Offers advice to administrators on how to encourage the teachers in their schools or districts and create a climate that allows them to take risks and act as coaches to their students.
A snotty situation ensues when Melvin Sneedley, an academically-gifted student, turns into the Bionic Booger Boy and must be stopped by George, Harold, and Captain Underpants.