Seventeen-year-old Kendall, who suffers from obsessive-compulsive disorder, lives with her parents on a potato farm in a tiny community in Montana, where two teenagers go missing within months of each other, with no explanation.
In a society that purges thirteen-year-olds who are creative, identical twins Aaron and Alex are separated, one to attend University while the other, supposedly Eliminated, finds himself in a wondrous place where youths hone their abilities and learn magic.
The magical world of Artim? is gone and the Unwanteds are looking to Alex Stowe for answers, but while his twin brother Aaron continues to build his army in Quill, a very dangerous common enemy is revealed.
Using her ability to tap into other people's dreams, eighteen-year-old Janie investigates an alleged sex ring at her high school that involves teachers using the date rape drug on students.
Sixteen-year-old Jules, whose family owns an Italian restaurant and has a history of mental illness, starts seeing a recurring vision about a rival restaurant, a truck crash, and forbidden love.
While eighteen-year-old Janie ponders her future with Cabe, knowing that her being a dream-catcher means eventual blindness and crippling, she encounters her past as the father she never knew is hospitalized with brain trauma and seems to need her help.
Ever since she was eight years old, high school student Janie Hannagan has been uncontrollably drawn into other people's dreams, but it is not until she befriends an elderly nursing home patient and becomes involved with an enigmatic fellow-student that she discovers her true power.
As the Wanteds, Unwanteds, and Necessaries struggle to adjust to changes in their society, Mr. Today begins training fourteen-year-old Alex to replace him as Artime's leader one day while Alex's disgraced twin, Aaron, connives to take over Quill.
Dak, Sera, and Riq find themselves in the United States in 1850 where they find out the SQ has taken control of the Underground Railroad, and Dak and Sara wonder who to trust while Riq tries to save the life of a young boy.