When he and the other volunteers at Dr. Mac's veterinary clinic go to help out at Quinn's Stables, David makes several serious mistakes and must prove he can be trusted before Mr. Quinn will let him even be around the spirited horse that David wants to ride.
While on a Florida vacation with Dr. Mac, Zoe, and Maggie, Brenna tries to rescue a baby manatee only to wind up in hot water with Dr. Mac and the local manatee rescue center.
With the help of her veterinarian grandmother and the other volunteers at the Wild at Heart Animal Clinic, eleven-year-old Maggie rescues sick puppies from an illegal puppy mill.
Zoe, having accustomed herself to life with her veterinarian grandmother and the flock of wild parrots that live in the backyard, is confused about her feelings when her mother arrives to take her to a new home in Los Angeles.
After treating an injured greyhound at her grandmother's veterinary clinic, thirteen-year-old Maggie learns about the abuse of greyhounds in the dog-racing industry and vows to put a stop to it.
Seeing Jane's dog, Yum-Yum, help cheer up children in a cancer ward makes Zoe think about having her puppy, Sneakers, trained to do therapy, too, especially when Yum-Yum becomes very ill.
Seeing Jane's dog, Yum-Yum, help cheer up children in a cancer ward makes Zoe think about having her puppy, Sneakers, trained to do therapy, too, especially when Yum-Yum becomes very ill.