Jo is the tomboy bookish one while Bethie is the feminine good girl, but together they have the perfect life as sisters growing up in 1950s Detroit. However, as they grow up, their lives unfold much differently than they ever could have guessed against the backdrop of America's struggles and major events in the following decades--Vietnam, Woodstock, the women's liberation movement--turning Bethie into the hippie wild child and Jo into a proper young mother. Somewhere along the way, both sisters begin to realize they have taken a wrong turn.