In weeks Massachusetts was overrun by an insidious virus that is spread by saliva. Rations are handed out as the commonwealth are placed under quarantine. Dr. Ramola, a pediatrician receives a call from her best friend Natalie, who is due to give birth in a matter of days. Natalie's husband was bit and Natalie herself as well. Her last chance of survival is to get to a hospital for a vaccine and to deliver her baby. Ramola knows she only has a few hours at most, as they fight for their lives through a hostile landscape.