Winry, Ed, and Alphonse go south in Search of Izumi Curtis, the master alchemist; however, an encounter with a pickpocket in the town of Rush Valley heads them down a different path.
When the laboratory explodes, Edward is injured and forced to start his investigation of the Philosopher's Stone conspiracy over again, and Lieutenant Colonel Maes Hughes stumbles upon a terrifying secret.
Ed struggles to overcome his mistrust of his estranged father in order to receive help in fighting Pride, while Mustang leads an attack in Central City.
