Y / Vaughan, Brian K

Collects issues forty-three through forty-eight of "Y: The Last Man" comics in which Yorick Brown, the last remaining man on Earth four years after a plague that killed all male mammals, teams up with a government operative and a biochemist to find and rescue his monkey Ampersand, whose DNA may hold the key to restoring the male population.

Yorick Brown, an unmotivated man who is the last of his kind, travels with his monkey, Ampersand, and searches for his girlfriend while traveling aboard a ship in the Pacific with Agent 355 and Dr. Allison Mann, who are trying to figure out the key to the future of humanity.

Yorick Brown, the last man on Earth, finds himself fighting for survival when he is placed in the care of retired government agent 711 in the backcountry of Colorado while his companions, cloning specialist Dr. Allison Mann and government agent 355, go in search of antibiotics for Brown's monkey Ampersand, the planet's only other living male.

As the last remaining Y-chromosome carriers on the planet, Yorrick and his pet monkey are the key to the fate of humanity; teamed up with a government agent and the world's premier bioengineer, they travel across the country, dodging the man-hating Daughters of the Amazon, who are determined to kill the last man on Earth.

When a plague kills every mammal that possesses a Y chromosome, only Yorick Brown and his pet male monkey mysteriously survive. Yorick becomes the most important person on Earth who may possess the key to unlocking the secret of the gender-specific disease, but when he attempts to find his love who is 7,000 miles away, new threats begin to close in on him.

A graphic novel depicting the fate of humanity after all his fellow men and male mammals have fallen victim to the male-killing plague on the planet and Yorick is the last man left on earth. Includes a sketchbook of preliminary character designs for the characters in the novel.

"In this final volume, Yorick and Agent 355 prepare for their ultimate quest to reunite the last man with his lost love, while the person, people or thing behind the disaster that wiped out half of humanity is revealed. Then, Yorick Brown's long journey through an Earth populated only by women comes to a dramatic, unexpected conclusion. Collects Y: THE LAST MAN #49-60"--.