Tandy Angel is, along with her brothers, a suspect in their parents' murder but having grown up under Malcolm and Maud Angel's perfectionist demands, Tandy decides she must clear the family name no matter what.
Daniel goes after number seven on the List of Alien Outlaws, whose destructive tendencies could lead to an attempt to take over the Earth, but first Daniel must find a way to enlist the aid of number seven's own son.
The time has come for Max, Fang, Iggy, Nudge, Gasman, and Angel to face their ultimate enemy and, despite many obstacles, try to save the world from a sinister plan to re-engineer a select population into a scientifically superior master race.
After a short stay with an FBI agent who gives them a chance to attend school and live a normal life, the six genetically-altered, winged youths head toward Florida and Max's ultimate destiny--to save the world, whether she wants to or not.
