Sunny Lewin is sent to live with her grandfather for the summer in Florida, where she befriends Buzz, a boy completely obsessed with comic books, and faces the secret behind why she is in Florida in the first place.
In 1935, when her mother gets a job housekeeping for a woman who does not like children, eleven-year-old Turtle is sent to stay with relatives she has never met in far away Key West, Florida.
When Babymouse decides to become president of the student council, she learns that there is more to running for office than being famous and in charge.
As tryouts for the school musical begin, Babymouse takes the starring role in several imaginary Broadway productions, which also feature her debonair new classmate, Henry the hedgehog.