Squish, a meek amoeba who loves the comic book exploits of his favorite hero, "Super Amoeba," tries to emulate him when his best friend is threatened by a bully.
At swim camp, Squish's new friend Basil helps him avoid learning to swim with pranks that sometimes go too far, but the comic book exploits of Squish's idol, "Super Amoeba," help him deal with Basil and conquer his fear.
When Babymouse decides to become president of the student council, she learns that there is more to running for office than being famous and in charge.
In 1935, when her mother gets a job housekeeping for a woman who does not like children, eleven-year-old Turtle is sent to stay with relatives she has never met in far away Key West, Florida.