After moving with his unbearable sister to Miami, Florida, Jack tries to break some of his bad habits but finds himself irresistibly drawn to things disgusting, gross, and weird.
To the constant disappointment of his mother and his teachers, Joey has trouble paying attention or controlling his mood swings when his prescription meds wear off and he starts getting worked up and acting wired.
When young smuggler Ray Jakes is sent to prison, he meets an Elvis Presley impersonator and the two become friends. After the two perform Christmas concerts at the wardens request, Jakes discovers Elvis made a deal with the warden to be paroled when they finished and Jakes fails at an attempted escape. But having evidence of police brutality of a criminal cop, Jakes is paroled and seeks a new life.
A young woman named Ivy, who made a shocking discovery in her small western Pennsylvania town when she was seven years old and learned a surprising secret nine years later, questions whether she has inherited the Rumbaugh curse of having excessive love for one's mother.
Joey, who is still taking medication to keep him from getting too wired, goes to spend the summer with the hard-drinking father he has never known and tries to help the baseball team he coaches win the championship.
Joey's father returns, calling himself Charles Heinz and apologizing for his past bad behavior, and he swears that once Joey and his mother change their names and help him fix up the old diner he has bought, their lives will change for the better.
The author relates how, as a young adult, he became a drug user and smuggler, was arrested, did time in prison, and eventually got out and went to college, all the while hoping to become a writer.
Joey tries to keep his life from degenerating into total chaos when his mother sends him to be home-schooled with a hostile blind girl, his divorced parents cannot stop fighting, and his grandmother is dying of emphysema.